Pseudoephedrine and hypothyroidism. Pseudoephedrine interacts with MAOIs, tricyclic antidepressants, phentermine, and caffeine. Patients already taking thyroid hormone have a very low risk of having any new thyroid-related problems develop if they take cough and cold medicines containing iodine. People with a thyroid problem, including hyperthyroidism or hypothyroidism, should use caution with Sudafed. This article presents an unusual case of Graves’ disease that decompensated into thyroid storm after the ingestion of an over-the-counter cold medication containing pseudoephedrine. Also, people with diabetes should be extra careful when consuming pseudoephedrine and caffeine together, because studies show the combination can raise blood sugar and increase body temperature. Cough, Cold, and Allergy Medicines Many over-the-counter decongestants have pseudoephedrine or phenylephrine. The phase IV clinical study analyzes which people have Thyroid diseases when taking Sudafed. Other drugs that have the same active ingredients (e. A phase IV clinical study of FDA data: drug interactions are found among 453 people who take Pseudoephedrine hydrochloride (pseudoephedrine hydrochloride) and Levothyroxine sodium (levothyroxine sodium). These ingredients can cause heart palpitations or raise your blood pressure. People may be at increased risk of cardiovascular side effects if they take pseudoephedrine or phenylephrine and levothyroxine. Phenylephrine and pseudoephedrine are generally safe decongestants to take with levothyroxine. Since you take levothyroxine for mild hypothyroidism, it’s important to monitor symptoms such as increased heart palpitations or nervousness. What is Levothyroxine thyroid? It is based on pseudoephedrine hydrochloride and levothyroxine sodium (the active ingredients of Pseudoephedrine hydrochloride and Levothyroxine thyroid, respectively), and Pseudoephedrine hydrochloride and Levothyroxine thyroid (the brand names). A phase IV clinical study of FDA data: drug interactions are found among 53 people who take Armour thyroid (thyroid tablets, usp) and Sudafed (pseudoephedrine hydrochloride). Learn about the risks and safer alternatives. People who are currently testing as hyper-thyroid aren't supposed take pseudoephedrine because it raises the heart rate - if we are hyperthyroid, then our heart rate is typically already too high. eHealthMe is studying from 12,943 Sudafed users for the drug's side effects, drug interactions, effectiveness and more. Hypothyroidism is managed with a synthetic form of thyroxine (T4) called levothyroxine, available under the brand names Synthroid or Levothroid. D. The extended-release formulation of pseudoephedrine (Sudafed 24 Hour) contains a non-deformable material. Synthroid (levothyroxine) is a medication used to treat hypothyroidism, an endocrine disorder in which the thyroid gland does not produce enough thyroid hormone. Examples of commonly used decongestants include phenylephrine and pseudoephedrine. Sudafed (pseudoephedrine) can interact with thyroid medications like levothyroxine, potentially increasing heart rate or blood pressure. generic drugs) are not considered. It’s important to consult your healthcare provider before combining these drugs. There have been rare reports of obstructive symptoms in patients with known strictures following the ingestion of similar sustained-release products. 3. Decongestants are medicines that can provide short-term relief for a blocked or stuffy nose (nasal congestion). [15][16][17] At higher doses, it may produce various additional effects A moderate drug interaction exists between 12 Hour Decongestant and NP Thyroid. , Afrinol) and Thyroid Extract, including interaction severity and how likely the interaction is to occur. Here’s what you should not take with pseudoephedrine to avoid side effects. Nov 17, 2025 · Some decongestants, like pseudoephedrine, can worsen heart issues in people with thyroid disorders. A moderate drug interaction exists between NP Thyroid and Pseudoephedrine. It is often used in nasal congestion. If your thyroid hormone levels are all within normal range, then you can check in with your Dr or pharmacist about taking pseudo-ephedrine. Come to us in your pursuit of wellness. Includes pseudoephedrine side effects, interactions, and indications. If you can't get a good night's sleep, your medication might be to blame. Zyrtec-D is a combination of cetirizine and pseudoephedrine. DEAR MAYO CLINIC: I’ve heard that nonprescription decongestants can have significant side effects. Here are 11 caffeine drug interactions to be cautious of. Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. Get powerful sinus congestion & pressure relief with SUDAFED® Sinus Congestion, formulated with pseudoephedrine HCl to help relieve swollen nasal passages. This medication is both an antihistamine and a decongestant. Here are OTC sinusitis medications that can help you feel better fast. If you have atrial fibrillation, here’s a list of medications you should avoid and why. Type 2 diabetes mellitus—Use of pseudoephedrine may cause an increase in blood glucose levels Enlarged prostate or Glaucoma, or a predisposition to glaucoma or Heart disease or blood vessel disease or High blood pressure—Pseudoephedrine may make the condition worse Overactive thyroid—Use of pseudoephedrine may make the condition worse A moderate drug interaction exists between Armour Thyroid and Pseudoephedrine. Find out about the different types and who can take them. g. Easy-to-read patient tips for pseudoephedrine covering how it works, benefits, risks, and best practices. Pseudoephedrine (Sudafed) and phenylephrine are common decongestants that work by constricting blood vessels in the nasal passages. These substances can impact heart and blood vessel function and may interfere with thyroid medications, specifically levothyroxine. Evidence-based interaction details between Pseudoephedrine Sulfate (brand name (s): Drixoral N. Apr 4, 2025 · Decongestants, particularly those containing pseudoephedrine, can pose risks for individuals with thyroid disorders, including hyperthyroidism and hypothyroidism. What is Sudafed? Sudafed has active ingredients of pseudoephedrine hydrochloride. You can sometimes give pseudoephedrine to children aged 6 years and over if they have a stuffy nose, but this depends on their symptoms. Hyperthyroidism: This condition causes an overactive thyroid, and pseudoephedrine may worsen symptoms such as increased heart rate and nervousness. Avoid decongestants such as oxymetazoline and ephedrine when on levothyroxine. Medications like Sudafed can keep you awake. The drugs are also available in several combinations with other over-the-counter cough and cold medications. . It treats symptoms of allergies. Hypothyroidism can cause symptoms like fatigue, weight gain, dry skin, hair loss, and sensitivity to cold temperatures. For more on how iodine may affect the thyroid, see Iodine. It is based on pseudoephedrine hydrochloride and levothyroxine sodium (the active ingredients of Pseudoephedrine hydrochloride and Levothyroxine thyroid, respectively), and Pseudoephedrine hydrochloride and Levothyroxine thyroid (the brand names). This article presents an unusual case of Graves' disease that decompensated into thyroid storm after the ingestion of an over-the-counter cold medication containing pseudoephedrine. Is this true? ANSWER: While many people rely on nasal decongestants to help ease symptoms of a cold or flu, these medications can sometimes cause more harm than good, especially if taken repeatedly. Find patient medical information for Pseudoephedrine (Sudafed, Zephrex-D, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Glaucoma: Pseudoephedrine can increase pressure in the eyes, which may worsen glaucoma, especially in patients with narrow-angle glaucoma. View detailed information regarding this drug interaction. Sudafed (pseudoephedrine) can raise blood pressure and heart rate, which may affect those with thyroid conditions like hypothyroidism. Ask a pharmacist for advice. Apr 13, 2025 · Nasal decongestants can generally be used by people with hypothyroidism, but caution is advised due to potential interactions and exacerbation of underlying conditions. Sinusitis, or sinus infection, can cause pain, pressure, and congestion in the sinuses. Type 2 diabetes mellitus—Use of pseudoephedrine may cause an increase in blood glucose levels Enlarged prostate or Glaucoma, or a predisposition to glaucoma or Heart disease or blood vessel disease or High blood pressure—Pseudoephedrine may make the condition worse Overactive thyroid—Use of pseudoephedrine may make the condition worse Summary: Thyroid diseases is reported as a side effect among people who take Sudafed (pseudoephedrine hydrochloride), especially for people who are female, 20-29 old, also take Imitrex, and have Birth control. Read on to learn how to beat drug-induced insomnia. If you have thyroid disease, heart disease, diabetes or an enlarged prostate, taking products containing pseudoephedrine or phenylephrine may worsen your condition. Pseudoephedrine should not be used by consumers with heart disease, high blood pressure, thyroid disease, diabetes or an enlarged prostate without talking with a health care provider like a Find patient medical information for Pseudoephedrine (Sudafed, Zephrex-D, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings I also saw this and consulted a pharmacist but didn’t get helpful guidance other than to monitor myself for cardiovascular effects if I decided to take pseudoephedrine for nasal congestion. Check Sudafed in the real world. Thyroid Sudafed (pseudoephedrine) can raise blood pressure and heart rate, which may affect those with thyroid conditions like hypothyroidism. Can levothyroxine cause sinus problems? Read everything you need to know about hypothyroid medications, sinuses, and decongestants here. Always talk to your doctor before taking decongestants if you have a thyroid disorder. Who can take pseudoephedrine Most adults and children aged 12 years and over can take pseudoephedrine. Ephedrine and pseudoephedrine are adrenergic medications and thyroid hormones have mainly a Betamimetic effect specially in the heart. Ingestion of sympathomimetic drugs in thyrotoxic individuals may precipitate thyroid storm. Certain medications and supplements can have side effects when taken with caffeine. Pseudoephedrine is a decongestant used to treat nasal congestion, sinus pressure or ear congestion caused by colds, flu, or allergies. Medscape - Indication-specific dosing for Sudafed, Nexafed, Zephrex-D (pseudoephedrine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Like caffeine, pseudoephedrine is also a stimulant. Sudafed contains pseudoephedrine, while Sudafed PE contains phenylephrine. [1][14][2] It has also been used off-label for certain other indications, like treatment of low blood pressure. We're committed to being your source for expert health guidance. Pseudoephedrine (Sudafed) is a nasal decongestant that can be purchased over the counter to help treat a stuffy nose from the common cold or allergies. […] Because coffee is also a stimulant, mixing it with cold and allergy medications can cause restlessness, jitteriness and sleep issues. A moderate drug interaction exists between 12 Hour Decongestant and NP Thyroid. nsjj, lwzhvg, japjyb, cioj4, t3mm0, c9upc, 2qtu1, rhfub, qgq529, uwn6h3,